Onglyza Lawsuits & Complications

Onglyza (generic name saxagliptin) is a prescription medicine used to reduce blood glucose in patients with type 2 diabetes.   This category of drugs helps the pancreas with insulin secretion and prevents the liver from producing surplus sugar.  However, the medication may be associated with serious complications such as heart failure and pancreatic cancer.

It has led several patients and their families to file lawsuits against the maker alleging improper testing and deceptive marketing and advertising practices, which they say contributed to their medical conditions.

Onglyza Uses

Onglyza was approved by the FDA for treating type 2 diabetes in adults.  When used together with appropriate diet and exercise, Onglyza can help lower blood glucose in diabetic patients.  Patients should monitor their glucose while taking the medication.  Onglyza isn’t for individuals with type 1 diabetes or diabetic ketoacidosis.

Onglyza and the Risk of Heart Failure

In April 2015, the FDA requested Onglyza to carry a warning about the danger of heart failure.  The SAVOR research discovered that of the almost 16,500 patients in the study, individuals who obtained Onglyza had a 27 percent higher risk of hospitalization for heart failure compared to the control group.  While heart failure isn’t always deadly, it can reduce quality of life and puts the individual at risk for much more cardiovascular complications.

Symptoms of heart failure include:

  • Difficulty breathing
  • Swelling of hands, feet, or ankles
  • Irregular heart rate
  • Fatigue
  • Persistent cough or wheezing

Onglyza and the Risk of Pancreatic Complications

In November 2011, the FDA added a warning to Onglyza concerning the risk of pancreatitis. This condition causes the pancreas to become inflamed and Critical instances can necessitate hospitalization or cause death.

Signs of pancreatitis may include:

  • Upper abdominal pain
  • Abdominal pain that radiates to your back or worsens after eating
  • Fever
  • Rapid pulse
  • Nausea and vomiting
  • Abdominal tenderness

The FDA warning educates physicians to discontinue Onglyza to their patients, if they suspect or diagnose pancreatitis.  Pancreatitis can boost the risk of pancreatic cancer, and this is now another concern with this medication.

The analysis found that DPP-4 medications such as Onglyza can raise the quantity and size of beta cells in the pancreas.  These cells might become abnormal and might form small, benign tumors which may become malignant.

Other Onglyza Side Effects and Complications

Onglyza lists frequent side effects for example:

  • Upper respiratory tract infections
  • Urinary tract infections
  • Headaches
  • Nausea, vomiting, diarrhea
  • Stuffy or runny nose
  • Sore throat

Side effects related to allergic reactions may include:

  • Swelling of the face, lips, or throat
  • Difficulty swallowing or breathing
  • Swelling of the skin
  • Hives, rash, itching, or flaking or peeling skin

Moreover, there are potential complications associated with Onglyza use with different drugs.  Patients taking another medicine to treat diabetes may experience low blood glucose.   Even supplements or vitamins can impact prescription medications such as Onglyza, therefore patients must notify their physician of all medicines they’re taking.  Patients who experience unwanted side effects or complications while carrying the medication should notify their physician immediately.

The Connection Between Onglyza and Kombiglyze XR

Kombiglyze XR is a combination drug containing Onglyza and Metformin, another popular diabetic medication. Patients taking this medicine have to know about precisely the very same risks as patients who take Onglyza alone.

Diabetic Drugs and Cardiovascular Risks

In 2008, the FDA published new recommendations for assessing Cardiovascular risks related to fresh type two diabetes medications, such as Onglyza.

Some medication like Onglyza met the basic criteria for reduced prevalence of heart attacks, the FDA called those initial tests into question. Onglyza’s maker, AstraZeneca, stated the drug decreased the risk of cardiovascular events and wished to incorporate this in the drug’s prescribing information.  On the other hand, the FDA denied the petition, citing lack of data.  Only after a pressure from the FDA AstraZeneca did perform broader post-marketing testing that demonstrated the heightened chance of heart failure.   This new data directed the FDA to take that the warning of heart failure on Onglyza substances.

If You Suffered Complications from Onglyza, You Might Have a Legal Case

Several patients and their families have filed lawsuits against Onglyza’s manufacturer, AstraZeneca. These lawsuits state AstraZeneca deceptively marketed Onglyza and didn’t sufficiently examine it prior to gaining acceptance and advertising the drug, therefore neglecting to recognize many possible dangers including heart failure.  If you are a patient who’s taking or has used Onglyza and suffer from any of these conditions, you may be qualified to submit a claim for damages.  Furthermore, in case you’ve got a relative who took Onglyza and passed away from one of these conditions, you may qualify for damages.

If successful, your claim may allow you to recover damages such as:

  • Medical costs
  • Lost earning potential and wages
  • Pain and suffering

Some plaintiffs are seeking punitive damages from the producer, which aim to punish the defendant and discourage future similar behavior.

Punitive damages are recoverable in cases of gross negligence, which some allege it has to do with AstraZeneca’s failure to property test Onglyza to identify complications like heart failure.

To find out more about the right to file a claim, talk to a lawyer.  Telephone 1-800-HURT-NOW for help locating an Attorney who will answer your damages.