Invokana Complications & Lawsuits

Invokana, generic name canagliflozin, is a medication used to treat type 2 diabetes.  The U.S. Food and Drug Administration (FDA) approved Invokana as the primary drug of its type (sodium-glucose co-transporter two (SGLT2) inhibitors).

One of the complications associated with the medication is ketoacidosis, a serious condition that could result in severe health difficulties, up to and including death.  Patients might also be at risk of kidney issues and other unpleasant side effects.

Invokana Uses

Invokana assists patients with type 2 diabetes to control blood sugar levels. It works by aiding the kidneys in eliminating blood in the body.  It does so by blocking SGLT2 carriers that usually reabsorb and release glucose back into the bloodstream.

Patients using Invokana, excrete excess sugar trough urination, rather than the sugar building up in their bloodstream.

Invokana Side Effects

Like any medication, Invokana may have certain side effects. Some possible side effects include:

  • Frequent and higher volume of urination
  • Getting up at night to urinate
  • Urinary tract infections
  • Vaginal yeast infections
  • Yeast infections of the penis
  • Dehydration

The FDA has also received reports of acute pancreatitis in patients using Invokana.  The agency is assessing whether to incorporate a warning of acute pancreatitis related to this and other SGLT2 inhibitors.  The patients with reported cases of acute pancreatitis had utilized Invokana before symptoms had begun, and symptoms subsided as patients received treatment and stopped taking Invokana.

Invokana may be associated with other, more serious complications too. This may include:

  • Diabetic ketoacidosis
  • Urinary tract infections
  • Acute kidney injury
  • Cardiovascular problems

Invokana and Diabetic Ketoacidosis

Since December 2015, the FDA requires Invokana along with other SGLT2 inhibitors to add a warning regarding the danger of diabetic ketoacidosis (DKA), a severe condition which can be deadly if left untreated.

DKA is a condition where the body is lacking insulin and therefore can’t use glucose for energy.  It instead starts to burn fat for energy, releasing ketones.  Ketones can be poisonous when they develop to high levels in blood.  Patients with DKA can experience symptoms like:

  • High blood sugar
  • Frequent urination
  • Thirst and dry mouth
  • Fatigue
  • Nausea, vomiting, abdominal pain
  • Trouble breathing
  • Breath with fruity odor
  • Difficulty concentrating
  • Confusion

Patients with symptoms of ketoacidosis require immediate medical attention.

Invokana and Urinary Tract Infection

The FDA also requires a warning about the increased risk of urinary tract infections (UTIs) associated with Invokana. UTIs can cause:

  • Burning during urination
  • Urgent need to urinate
  • Frequent urination
  • Pain or pressure in the pelvis
  • Bloody urine

The FDA also warns about the possible progression of UTIs into blood ailments without appropriate treatments.  Indicators of blood infections may include:

  • Rapid breathing
  • Fever
  • Pale complexion
  • Chills
  • Heart palpitations
  • Increased heart rate

Blood infections can be fatal if untreated, so it is important to seek emergency medical care right away.

Invokana and Acute Kidney Injury

In June 2016, the FDA requested a warning about the risk of acute kidney injury (AKI). Acute kidney injury is a condition where the kidneys cease to function, causing a potentially fatal buildup of waste. Symptoms of AKI include:

  • Chest pain
  • Coma
  • Confusion
  • Fatigue
  • Nausea
  • Seizures
  • Shortness of breath
  • Swelling around the eyes
  • Swelling in legs and ankles
  • Very little urination

Patients Using AKI may require hospitalization to get treatment, which might consist of dialysis.  AKI also raises the chance of kidney disease and kidney failure.

Invokana and Adverse Cardiovascular Events

Upon the drug’s approval, the FDA required Johnson & Johnson to track adverse cardiovascular events associated with the drug, and to complete the Cardiovascular Assessment Study (CANVAS), which began in 2009.

The CANVAS trial includes over 4,300 participants who have cardiovascular disease or are at risk for it. While the study is not yet finished, preliminary data suggests a 46 percent increase in the risk of stroke for the first 30 days of taking the drug.

Finding a Lawsuit for Complications of Invokana

Although, Invokana can cause a lot of serious complications and side effects, the focus of recent lawsuits is on ketoacidosis.

These lawsuits claim there was an insufficient warning regarding the dangers of DKA.   Some plaintiffs required hospitalization and significant treatment for medical conditions they state are linked with Invokana.

If you or a loved one took Invokana, you might have a legal claim if you experienced any of the following:

Diabetic ketoacidosis

  • Blood clots or infections
  • Stroke
  • Acute kidney injury
  • Acute pancreatitis

If your lawsuit is successful, you may recover compensation for your damages, which may include:

  • Medical expenses associated with your health condition
  • Lost wages and earning potential
  • Pain and suffering and other noneconomic damages

These are just examples.  Based upon your case, you could be qualified to recover payment for other damages also.  To review the damages you may be able to recover and determine your eligibility to submit an Invokana lawsuit, speak with a lawyer who can provide help.

Call (914) 200-0013 for assistance locating a lawyer who can answer your questions and help you pursue a lawsuit for your losses and expenses.